Jan W Drijfhout Selected Research

monobenzone (Benoquin)

1/2018	Anti-Melanoma immunity and local regression of cutaneous metastases in melanoma patients treated with monobenzone and imiquimod; a phase 2 a trial.
6/2011	Skin-depigmenting agent monobenzone induces potent T-cell autoimmunity toward pigmented cells by tyrosinase haptenation and melanosome autophagy.

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Jan W Drijfhout Research Topics

Disease

18	Neoplasms (Cancer) 10/2021 - 11/2003
13	Rheumatoid Arthritis 05/2021 - 09/2005
13	Infections 01/2020 - 02/2010
8	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2019 - 12/2005
7	Celiac Disease (Celiac Sprue) 05/2014 - 09/2008
5	Melanoma (Melanoma, Malignant) 01/2018 - 01/2011
5	Neoplasm Metastasis (Metastasis) 01/2018 - 06/2008
5	Colorectal Neoplasms (Colorectal Cancer) 04/2013 - 11/2003
4	Inflammation (Inflammations) 01/2021 - 10/2008
4	Arthritis (Polyarthritis) 02/2012 - 09/2005
3	Wounds and Injuries (Trauma) 12/2019 - 08/2014
3	Graft vs Host Disease (Graft-Versus-Host Disease) 04/2013 - 04/2002
3	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2012 - 01/2008
3	Autoimmune Diseases (Autoimmune Disease) 09/2008 - 09/2005
2	Vitiligo 01/2018 - 06/2011
2	Disease Progression 04/2016 - 03/2016
2	Cardiovascular Diseases (Cardiovascular Disease) 09/2014 - 03/2014
2	Aspergillosis 07/2014 - 09/2013
2	Ovarian Neoplasms (Ovarian Cancer) 09/2012 - 11/2009
2	Tuberculosis (Tuberculoses) 10/2011 - 02/2010
2	Carcinoma (Carcinomatosis) 06/2008 - 10/2006
1	Herpes Simplex 01/2020
1	Suppurative Otitis Media 01/2020
1	Virus Diseases (Viral Diseases) 01/2020
1	Wound Infection (Wound Infections) 01/2020
1	Atherosclerosis 11/2019
1	Staphylococcal Infections 10/2018
1	Tetanus 01/2018
1	Polyploidy 11/2017
1	Hypoxia (Hypoxemia) 01/2017
1	Insulinoma 04/2016

Drug/Important Bio-Agent (IBA)

35	Peptides (Polypeptides)IBA 01/2020 - 12/2005
17	AntigensIBA 01/2021 - 09/2005
13	Proteins (Proteins, Gene)FDA Link 05/2021 - 06/2007
11	EpitopesIBA 01/2019 - 08/2006
11	VaccinesIBA 04/2013 - 11/2003
7	AntibodiesIBA 05/2021 - 01/2010
6	AutoantibodiesIBA 06/2017 - 09/2005
5	AutoantigensIBA 01/2021 - 08/2006
5	Glutens (Glutelin)IBA 05/2014 - 10/2008
4	CytokinesIBA 09/2011 - 08/2006
3	Anti-Bacterial Agents (Antibiotics)IBA 10/2018 - 05/2012
3	preproinsulinIBA 04/2016 - 10/2008
3	HLA Antigens (Human Leukocyte Antigens)IBA 05/2014 - 01/2012
3	HLA-DQ Antigens (HLA-DQ)IBA 01/2014 - 09/2008
3	HLA-DQ8 antigenIBA 03/2012 - 09/2008
3	TroVax (5T4 cancer vaccine)IBA 10/2009 - 06/2008
2	Pharmaceutical PreparationsIBA 01/2020 - 08/2010
2	Hypromellose DerivativesIBA 01/2020 - 10/2018
2	Antimicrobial PeptidesIBA 01/2020 - 05/2012
2	HLA-A2 Antigen (HLA A2 Antigen)IBA 11/2019 - 09/2011
2	Lipoproteins (Lipoprotein)IBA 11/2019 - 01/2016
2	Immunoglobulin G (IgG)IBA 01/2018 - 01/2008
2	Imiquimod (Aldara)FDA LinkGeneric 01/2018 - 07/2005
2	monobenzone (Benoquin)FDA Link 01/2018 - 06/2011
2	HLA-B Antigens (HLA-B)IBA 11/2017 - 08/2010
2	Histocompatibility Antigens Class IIBA 11/2017 - 08/2010
2	RNA (Ribonucleic Acid)IBA 01/2017 - 08/2010
2	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 04/2016 - 01/2010
2	InterferonsIBA 07/2014 - 04/2013
2	Monatide (IMS 3015)IBA 03/2014 - 01/2008
2	Glucose (Dextrose)FDA LinkGeneric 01/2012 - 10/2008
2	HLA-A*02:01 antigenIBA 01/2012 - 10/2006
2	EnzymesIBA 01/2012 - 02/2009
2	Differentiation AntigensIBA 09/2011 - 06/2011
2	Monophenol Monooxygenase (Tyrosinase)IBA 09/2011 - 06/2011
2	p53 synthetic long peptide vaccineIBA 11/2009 - 02/2009
2	Insulin (Novolin)FDA Link 10/2008 - 12/2005
2	CitrullineIBA 10/2007 - 06/2007
1	HLA-A Antigens (HLA-A)IBA 10/2021
1	Anti-Idiotypic AntibodiesIBA 05/2021
1	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 01/2021
1	Immunoglobulin M (IgM)IBA 01/2021
1	Antiviral Agents (Antivirals)IBA 01/2020
1	Anti-Infective Agents (Microbicides)IBA 01/2020
1	PhosphatidylserinesIBA 01/2020
1	SolutionsIBA 12/2019
1	CholesterolIBA 11/2019
1	HLA-DQ6 antigenIBA 01/2019
1	Ointments (Pastes)IBA 10/2018
1	Gentamicins (Gentamicin)FDA LinkGeneric 10/2018
1	Melanoma-Specific AntigensIBA 01/2018
1	Antigen-Antibody Complex (Immune Complex)IBA 01/2018
1	OvalbuminIBA 01/2018
1	TrypsinIBA 06/2017
1	Biocompatible Materials (Biomaterials)IBA 01/2017
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2017
1	AntioxidantsIBA 01/2017
1	Transcription Factors (Transcription Factor)IBA 01/2017
1	Caspofungin (Cancidas)FDA Link 01/2017
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2017
1	DefensinsIBA 01/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2017
1	HLA-DR3 Antigen (HLA DR3 Antigen)IBA 04/2016
1	Glutamate Decarboxylase (Decarboxylase, Glutamate)IBA 04/2016

Therapy/Procedure

7	Immunotherapy 01/2018 - 10/2006
5	Therapeutics 01/2018 - 10/2008
3	Stem Cell Transplantation 07/2014 - 04/2013
1	Drug Therapy (Chemotherapy) 01/2017
1	Operative Surgical Procedures 01/2017